Title : Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed.

Pub. Date : 2000 May

PMID : 10785598






2 Functional Relationships(s)
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1 Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed. raltitrexed tumor protein p53 Homo sapiens
2 TS induction was highest after ZD1694 exposure in the mt p53 cells HT29 and WiDr/F (6-10-fold). raltitrexed tumor protein p53 Homo sapiens