Pub. Date : 2000 May
PMID : 10783125
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bleomycin-mediated pulmonary toxicity: evidence for a p53-mediated response. | Bleomycin | transformation related protein 53, pseudogene | Mus musculus |
| 2 | p53-positive cells first appeared at 5 d after treatment and peaked at 7 d; PCNA-positive cells appeared at 1 d after treatment and peaked at 7 d; and p21-positive cells appeared at 5 d and peaked at 9 d. Western blot analysis confirmed that bleomycin upregulated the DNA damage-inducible proteins in a similar fashion. | Bleomycin | transformation related protein 53, pseudogene | Mus musculus |
| 3 | This is the first evidence that bleomycin causes a p53-dependent response associated with acute injury in the lung. | Bleomycin | transformation related protein 53, pseudogene | Mus musculus |