Title : HIV-1 Tat increases endothelial solute permeability through tyrosine kinase and mitogen-activated protein kinase-dependent pathways.

Pub. Date : 2000 Mar 31

PMID : 10780709






1 Functional Relationships(s)
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1 RESULTS: Tat-1 significantly reduced monolayer barrier and increased albumin permeability within 24 h. Tat-1 also stimulated tyrosine phosphorylation of multiple endothelial proteins, disorganized junctional phosphotyrosine staining and increased the number of these immunostaining structures. Tyrosine solute carrier family 26 member 8 Homo sapiens