Pub. Date : 2000 Jul 7
PMID : 10779504
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. | Cyclic AMP | androgen receptor | Homo sapiens |
2 | p300 and p300/cAMP-response element-binding protein acetylated the AR at a highly conserved lysine-rich motif carboxyl-terminal to the zinc finger DNA-binding domain. | Cyclic AMP | androgen receptor | Homo sapiens |
3 | Mutation of the p300 CH3 region or the p300/cAMP-response element-binding protein histone acetylase domain reduced ligand-dependent AR function. | Cyclic AMP | androgen receptor | Homo sapiens |