Title : Agkistin, a snake venom-derived glycoprotein Ib antagonist, disrupts von Willebrand factor-endothelial cell interaction and inhibits angiogenesis.

Pub. Date : 2000 Jun 23

PMID : 10779501






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 AP1, a monoclonal antibody (mAb) raised against GPIb, specifically inhibited the binding of FITC-conjugated agkistin to HUVECs in a dose-dependent manner, but other anti-integrin mAbs raised against alpha(v)beta(3), alpha(2)beta(1), and alpha(5)beta(1) did not affect this binding reaction. Fluorescein-5-isothiocyanate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens