Title : Direct evidence for decreased sialylation and galactosylation of human serum IgA1 Fc O-glycosylated hinge peptides in IgA nephropathy by mass spectrometry.

Pub. Date : 2000 Apr 29

PMID : 10777713






1 Functional Relationships(s)
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1 The results obtained clearly showed a decrease of GalNAc, Gal, and sialic acid in IgAN compared with non-IgAN and normal controls, and those strongly suggested the possibility that the decreased galactosylation and sialylation of the IgA1 hinge result in its glomerular deposition in IgAN. N-acetylgalactosaminuronic acid IGAN1 Homo sapiens