Pub. Date : 2000 Jul 14
PMID : 10777488
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The same elevated levels of mRNA were maintained after 24 h of stimulation with insulin, whereas IGF-I treatment further increased VEGF mRNA expression to 12-fold after 24 h. Pre-incubation with the phosphatidylinositol 3-kinase inhibitor wortmannin abolished the effect of insulin on VEGF mRNA expression in NIH-IR cells but did not modify the IGF-I-induced VEGF mRNA expression in NIH-IGFR cells. | Phosphatidylinositols | insulin like growth factor 1 | Homo sapiens |