Pub. Date : 2000 Apr 15
PMID : 10766914
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The isoflavone genistein may either stimulate or inhibit cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channels. | Genistein | cystic fibrosis transmembrane conductance regulator | Mus musculus |
| 2 | The isoflavone genistein may either stimulate or inhibit cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channels. | Genistein | cystic fibrosis transmembrane conductance regulator | Mus musculus |
| 3 | Single-channel analysis of channel block suggested that genistein (100 microM) may inhibit CFTR by two mechanisms: first, it may slow the rate of channel opening and second, it may block open channels. | Genistein | cystic fibrosis transmembrane conductance regulator | Mus musculus |
| 4 | Acidification of the intracellular solution relieved channel block, suggesting that the anionic form of genistein may inhibit CFTR. | Genistein | cystic fibrosis transmembrane conductance regulator | Mus musculus |