Title : Effects of gemcitabine and araC on in vitro DNA synthesis mediated by the human breast cell DNA synthesome.

Pub. Date : 2000

PMID : 10755321






1 Functional Relationships(s)
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1 It was found that the drug concentrations required to inhibit 50% of the synthesome-associated DNA polymerase delta activity were much higher than those required to inhibit 50% of DNA polymerase alpha activity for both dFdCTP and araCTP. Arabinofuranosylcytosine Triphosphate DNA polymerase alpha 1, catalytic subunit Homo sapiens