Title : Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis.

Pub. Date : 2000 Mar 1

PMID : 10754270






2 Functional Relationships(s)
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1 Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis. 7-ketocholesterol cytochrome c, somatic Homo sapiens
2 Previous investigations of our laboratory have shown that 7-ketocholesterol was a potent inducer of apoptosis involving a release of cytochrome c into the cytosol, and a lipid peroxidation process that could be the consequence of a production of radical oxygen species. 7-ketocholesterol cytochrome c, somatic Homo sapiens