Title : Activation of NF-kappaB by FADD, Casper, and caspase-8.

Pub. Date : 2000 Apr 14

PMID : 10753878






1 Functional Relationships(s)
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1 A mutant of Casper and the caspase-specific inhibitors crmA and BD-fmk partially inhibit TNF-R1-, TRADD, and TNF-induced NF-kappaB activation, suggesting that FADD, Casper, and caspase-8 function downstream of TRADD and contribute to TNF-R1-induced NF-kappaB activation. bd-fmk tumor necrosis factor Homo sapiens