Title : Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells.

Pub. Date : 2000 May 26

PMID : 10747891






1 Functional Relationships(s)
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Protein Name
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1 The early generation of ceramide preceded transient activation of acidic ceramidase and subsequent production of sphingosine, followed by cytochrome c release, activation of caspases-2, -3, -6, -7, -8, and -9, Bid cleavage, and a later sustained ceramide accumulation. Ceramides caspase 2 Homo sapiens