Title : [Effect of eosinophil major basic protein on histamine release from nasal epithelial mast cells].

Pub. Date : 1997 Aug

PMID : 10743163






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The activity of the eosinophil cationic protein, major basic protein (MBP) on histamine release from human NEMCs has not been documented. Histamine myelin basic protein Homo sapiens
2 We examined the effects of MBP on histamine release from NEMCs. Histamine myelin basic protein Homo sapiens
3 MBP at the concentration of 10(-5) mol/L induced mild but statistically significant histamine release from the NEMCs. Histamine myelin basic protein Homo sapiens
4 Preincubation with MBP at the concentration of 1.57 x 10(-5) mol/L produced slight inhibition of subsequent HDM-induced histamine release but preincubation with HDM showed no effect on the subsequent MBP-induced or HDM-induced histamine release from NEMCs. Histamine myelin basic protein Homo sapiens
5 Preincubation with MBP at the concentration of 1.57 x 10(-5) mol/L produced slight inhibition of subsequent HDM-induced histamine release but preincubation with HDM showed no effect on the subsequent MBP-induced or HDM-induced histamine release from NEMCs. Histamine myelin basic protein Homo sapiens