Pub. Date : 2000 Mar
PMID : 10731712
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Promotion of the uptake of PS liposomes and apoptotic cells by a product of growth arrest-specific gene, gas6. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |
| 2 | In our previous study, we demonstrated that Gas6 specifically binds to phosphatidylserine (PS) and links Axl-expressing cells to the PS-coated surface. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |
| 3 | In our previous study, we demonstrated that Gas6 specifically binds to phosphatidylserine (PS) and links Axl-expressing cells to the PS-coated surface. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |
| 4 | In our previous study, we demonstrated that Gas6 specifically binds to phosphatidylserine (PS) and links Axl-expressing cells to the PS-coated surface. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |
| 5 | In this study, to further understand the biological role of the interaction of Gas6 with PS, we examined the effect of Gas6 on the uptake of PS liposomes by macrophages. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |
| 6 | In vitro phagocytosis studies showed that Gas6 enhanced the uptake of PS liposomes approximately threefold and that the interaction of Gas6 with the surface of macrophages was essential for this enhancement. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |
| 7 | Analyses of the mechanism of the uptake of PS liposome suggested that Gas6 interacts with PS liposome via its N-terminal Gla domain and with macrophages via its C-terminal domain. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |
| 8 | Analyses of the mechanism of the uptake of PS liposome suggested that Gas6 interacts with PS liposome via its N-terminal Gla domain and with macrophages via its C-terminal domain. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |
| 9 | Like that of PS liposomes, the uptake of apoptotic cells by macrophages was also enhanced, approximately twofold, in the presence of Gas6. | Phosphatidylserines | growth arrest specific 6 | Homo sapiens |