Title : Partial purification and characterization of a wortmannin-sensitive and insulin-stimulated protein kinase that activates heart 6-phosphofructo-2-kinase.

Pub. Date : 2000 Apr 1

PMID : 10727432






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 WISK phosphorylated recombinant heart PFK-2 in a time-dependent manner to the extent of 0.4 mol of phosphate incorporated/mol of enzyme subunit, and increased the V(max) of PFK-2 twofold, without affecting the K(m) for fructose 6-phosphate. fructose-6-phosphate 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 Rattus norvegicus