Title : Evolution of a glucose-regulated ADH gene in the genus Saccharomyces.

Pub. Date : 2000 Mar 21

PMID : 10717481






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 To determine when a glucose-repressed alcohol dehydrogenase isozyme and its regulatory gene, ADR1, arose during evolution, we surveyed species of the genus Saccharomyces for glucose-repressed ADH isozymes and for ADR1 homologues. Glucose DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C
2 To determine when a glucose-repressed alcohol dehydrogenase isozyme and its regulatory gene, ADR1, arose during evolution, we surveyed species of the genus Saccharomyces for glucose-repressed ADH isozymes and for ADR1 homologues. Glucose DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C
3 To determine when a glucose-repressed alcohol dehydrogenase isozyme and its regulatory gene, ADR1, arose during evolution, we surveyed species of the genus Saccharomyces for glucose-repressed ADH isozymes and for ADR1 homologues. Glucose DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C
4 The expression of a reporter gene driven by the S. bayanus promoter was glucose-repressed and dependent on the major activator of transcription, ADR1, when it was introduced into S. cerevisiae. Glucose DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C
5 Although showing little sequence conservation with the S. cerevisiae ADH2 promoter, the glucose-repressed S. kluyveri promoter contains numerous potential binding sites for Adr1. Glucose DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C