Pub. Date : 2000 Mar 1
PMID : 10711524
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It appears to block cell-cycle progression in the mid-to-late G1 phase; it also inhibits interleukin-2-dependent and independent proliferation of B-lymphocytes and production of immunoglobulins A, M, and G. Sirolimus is extensively metabolized by the liver and undergoes O-demethylation and hydroxylation. | Sirolimus | interleukin 2 | Homo sapiens |