Title : Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.

Pub. Date : 2000 Mar 1

PMID : 10698924






1 Functional Relationships(s)
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1 Three crystal structures of the catalytic portion of human HMGR in complexes with HMG-CoA, with HMG and CoA, and with HMG, CoA and NADP(+), provide a detailed view of the enzyme active site. NADP 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens