Title : Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.

Pub. Date : 2000 Feb 17

PMID : 10693811






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Here we show that yeast and mouse Sir2 proteins are nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylases, which deacetylate lysines 9 and 14 of H3 and specifically lysine 16 of H4. NAD sirtuin 1 Mus musculus
2 Here we show that yeast and mouse Sir2 proteins are nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylases, which deacetylate lysines 9 and 14 of H3 and specifically lysine 16 of H4. NAD sirtuin 1 Mus musculus