Title : Molecular basis of a progressive juvenile-onset hereditary cataract.

Pub. Date : 2000 Feb 29

PMID : 10688888






1 Functional Relationships(s)
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1 We have expressed recombinant wild-type human gammaD crystallin (HGD) and its Arg-14 to Cys mutant (R14C) in Escherichia coli and show that R14C forms disulfide-linked oligomers, which markedly raise the phase separation temperature of the protein solution. Disulfides crystallin gamma D Homo sapiens