Title : Methylation of the human telomerase gene CpG island.

Pub. Date : 2000 Feb 1

PMID : 10676632






1 Functional Relationships(s)
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1 Together, these data show that the hTERT CpG island can undergo cytosine methylation in cultured cells and tumors and that DNA methylation may contribute to the regulation of the hTERT gene, but that CpG island methylation is not responsible for repressing hTERT expression in most telomerase-negative cells. Cytosine telomerase reverse transcriptase Homo sapiens