Title : NPC1-containing compartment of human granulosa-lutein cells: a role in the intracellular trafficking of cholesterol supporting steroidogenesis.

Pub. Date : 2000 Feb 25

PMID : 10666334






1 Functional Relationships(s)
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1 Incubation of granulosa-lutein cells with low-density lipoprotein (LDL) in the presence of the hydrophobic amine, U18666A, caused accumulation of free cholesterol in granules, identified by filipin staining, that contained LAMP-2 and NPC1. Amines NPC intracellular cholesterol transporter 1 Homo sapiens