Title : Permeation and gating residues in serotonin transporter.

Pub. Date : 2000 Feb 1

PMID : 10655481






3 Functional Relationships(s)
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1 The third transmembrane domain (TM3) of serotonin transporter (SERT) contains two isoleucine residues previously proposed to be involved in binding and transport of serotonin. Isoleucine tropomyosin 3 Homo sapiens
2 They also suggest that Ile-179 in SERT (and Ile-155 in NET) is in a conformationally sensitive part of TM3, which may act as part of an external gate. Isoleucine tropomyosin 3 Homo sapiens
3 They also suggest that Ile-179 in SERT (and Ile-155 in NET) is in a conformationally sensitive part of TM3, which may act as part of an external gate. Isoleucine tropomyosin 3 Homo sapiens