Title : A model using radiation and plasmid-mediated tumor necrosis factor-alpha gene therapy for treatment of glioblastomas.

Pub. Date : 1999 Jul-Aug

PMID : 10652573






3 Functional Relationships(s)
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1 Subcutaneously growing tumors were injected with pGL1-TNF-alpha complexed with a cationic polyamine and radiation, singly and in combination, over an 8-day period. Polyamines tumor necrosis factor Homo sapiens
2 The maximum antitumor effect was achieved with the combination of polyamine-pGL1-TNF-alpha and radiation. Polyamines tumor necrosis factor Homo sapiens
3 The results demonstrate that polyamine-pGL1-TNF-alpha can be safely and effectively administered together with radiation under the conditions used. Polyamines tumor necrosis factor Homo sapiens