Title : The carboxyl terminus of the cystic fibrosis transmembrane conductance regulator binds to AP-2 clathrin adaptors.

Pub. Date : 2000 Feb 4

PMID : 10652362






1 Functional Relationships(s)
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1 Together, these data suggest that the carboxyl terminus of CFTR contains a tyrosine-based internalization signal that interacts with the endocytic adaptor complex AP-2 to facilitate efficient entry of CFTR into clathrin-coated vesicles. Tyrosine transcription factor AP-2 alpha Homo sapiens