Title : Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade.

Pub. Date : 2000 Jan 21

PMID : 10636929






1 Functional Relationships(s)
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1 First, the inositide-binding pocket of the Itk pleckstrin homology domain directs the constitutive association of Itk with buoyant membranes that are the primary site of TCR activation and are enriched in both Lck and LAT. inositide linker for activation of T cells Homo sapiens