Title : Effects of deltamethrin on nitric oxide synthase and poly(ADP-ribose) polymerase in rat brain.

Pub. Date : 1999 Dec 11

PMID : 10629771






11 Functional Relationships(s)
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1 Effects of deltamethrin on nitric oxide synthase and poly(ADP-ribose) polymerase in rat brain. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
2 The effects of deltamethrin on the activities of nitric oxide synthase (NOS) and poly(ADP-ribose) polymerase (PARP) and the protein expression of neuronal NOS (nNOS) and PARP in rat brain were investigated in the present study. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
3 The effects of deltamethrin on the activities of nitric oxide synthase (NOS) and poly(ADP-ribose) polymerase (PARP) and the protein expression of neuronal NOS (nNOS) and PARP in rat brain were investigated in the present study. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
4 The activity of NOS was significantly increased in cortex and hippocampus at 5 h after deltamethrin treatment, and maintained at an increased level at 24 h. The activity of PARP was also elevated at the same time points in the same brain regions of treated rats. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
5 The immunoreactivity for PARP was also increased in the same brain regions, showing the similar time course of the induction of nNOS by deltamethrin. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
6 These results indicate that deltamethrin increases the activities of NOS and PARP and initiates the protein expression of nNOS and PARP, suggesting that NOS and PARP might play important roles in neurotoxicity of deltamethrin. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
7 These results indicate that deltamethrin increases the activities of NOS and PARP and initiates the protein expression of nNOS and PARP, suggesting that NOS and PARP might play important roles in neurotoxicity of deltamethrin. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
8 These results indicate that deltamethrin increases the activities of NOS and PARP and initiates the protein expression of nNOS and PARP, suggesting that NOS and PARP might play important roles in neurotoxicity of deltamethrin. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
9 These results indicate that deltamethrin increases the activities of NOS and PARP and initiates the protein expression of nNOS and PARP, suggesting that NOS and PARP might play important roles in neurotoxicity of deltamethrin. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
10 These results indicate that deltamethrin increases the activities of NOS and PARP and initiates the protein expression of nNOS and PARP, suggesting that NOS and PARP might play important roles in neurotoxicity of deltamethrin. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus
11 These results indicate that deltamethrin increases the activities of NOS and PARP and initiates the protein expression of nNOS and PARP, suggesting that NOS and PARP might play important roles in neurotoxicity of deltamethrin. decamethrin poly (ADP-ribose) polymerase 1 Rattus norvegicus