Title : Effects of intestinal fatty acid-binding protein overexpression on fatty acid metabolism in Caco-2 cells.

Pub. Date : 2000 Jan

PMID : 10627505






4 Functional Relationships(s)
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1 Indeed, different effects on fatty acid metabolism depending on the cell type and the amount of I-FABP expressed have been reported. Fatty Acids fatty acid binding protein 2 Homo sapiens
2 Furthermore, a decrease in fatty acid incorporation has been unexpectedly obtained when I-FABP reached 0. Fatty Acids fatty acid binding protein 2 Homo sapiens
3 A nonsignificant 21% reduction of fatty acid incorporation was observed with another clone expressing 10-fold less I-FABP. Fatty Acids fatty acid binding protein 2 Homo sapiens
4 In conclusion, a high level of I-FABP expressed in a differentiated enterocyte model inhibited fatty acid incorporation, by a mechanism which remains to be defined. Fatty Acids fatty acid binding protein 2 Homo sapiens