Title : Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11.

Pub. Date : 1999 Dec 15

PMID : 10626806






3 Functional Relationships(s)
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1 Colon carcinoma cell lines could be further sensitized to TRAIL-induced apoptosis in vitro by the addition of the chemotherapeutic agent camptothecin. Camptothecin TNF superfamily member 10 Homo sapiens
2 Moreover, the combination of TRAIL and CPT-11, a water-soluble analogue of camptothecin, greatly enhanced the antitumor activity of TRAIL in vivo. Camptothecin TNF superfamily member 10 Homo sapiens
3 Moreover, the combination of TRAIL and CPT-11, a water-soluble analogue of camptothecin, greatly enhanced the antitumor activity of TRAIL in vivo. Camptothecin TNF superfamily member 10 Homo sapiens