Pub. Date : 1999 Sep-Oct
PMID : 10622400
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Progesterone inhibits intracellular transport of lysosomal cholesterol in cultured cells, and thus at least in part mimics the biochemical phenotype of Niemann-Pick type C disease (NPC) in human fibroblasts. | Progesterone | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 2 | Progesterone also partially inhibited 25-hydroxycholesterol-induced cholesterol esterification, with similar dose-dependence in normal and NPC fibroblasts. | Progesterone | NPC intracellular cholesterol transporter 1 | Homo sapiens |