Title : Progesterone metabolism in human fibroblasts is independent of P-glycoprotein levels and Niemann-Pick type C disease.

Pub. Date : 1999 Sep-Oct

PMID : 10622400






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 Progesterone inhibits intracellular transport of lysosomal cholesterol in cultured cells, and thus at least in part mimics the biochemical phenotype of Niemann-Pick type C disease (NPC) in human fibroblasts. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens