Pub. Date : 1999 Dec
PMID : 10600936
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In rOCT2 cRNA-injected oocytes, uptake of [14C]TEA was saturable, with an estimated Michaelis constant (Km) of 393 microM, and was specifically inhibited by organic cations. | Tetraethylammonium | solute carrier family 22 member 2 | Rattus norvegicus |
| 2 | Consistent with the potential sensitivity of uptake, electrophysiological analysis of rOCT2-injected oocytes demonstrated movement of positive charge into the oocyte upon TEA addition. | Tetraethylammonium | solute carrier family 22 member 2 | Rattus norvegicus |
| 3 | A stably transfected single cell clone (MDCK-rOCT2) showed mediated, potential-sensitive, pH-sensitive TEA uptake (Km = 48 microM). | Tetraethylammonium | solute carrier family 22 member 2 | Rattus norvegicus |
| 4 | TEA efflux from preloaded MDCK-rOCT2 cells was stimulated by externally applied (trans) tetramethylammonium but was trans-inhibited by H+ (external pH 5.4). | Tetraethylammonium | solute carrier family 22 member 2 | Rattus norvegicus |