Title : Effects of nicotine on cultured cells suggest that it can influence the formation and resorption of bone.

Pub. Date : 1999 Nov 3

PMID : 10594333






2 Functional Relationships(s)
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1 By contrast, nicotine reduced, in a dose-dependent manner, the formation of tartrate-resistant acid phosphatase (TRAP)-positive multinucleated cells (MNCs) and the formation of pits on slices of dentine, both of which are typical characteristics of osteoclasts. Nicotine acid phosphatase 5, tartrate resistant Mus musculus
2 By contrast, nicotine reduced, in a dose-dependent manner, the formation of tartrate-resistant acid phosphatase (TRAP)-positive multinucleated cells (MNCs) and the formation of pits on slices of dentine, both of which are typical characteristics of osteoclasts. Nicotine acid phosphatase 5, tartrate resistant Mus musculus