Title : Structure-activity studies of cerulenin analogues as protein palmitoylation inhibitors.

Pub. Date : 1999 Dec 2

PMID : 10585203






1 Functional Relationships(s)
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1 We have demonstrated that the natural product cerulenin ([2R,3S]-2,3-epoxy-4-oxo-7,10-trans,trans-dodecadienamide) inhibits the palmitoylation of H-ras- and N-ras-encoded p21s in parallel with inhibition of cell proliferation. Cerulenin H3 histone pseudogene 16 Homo sapiens