Title : Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin.

Pub. Date : 1999 Oct

PMID : 10583023






1 Functional Relationships(s)
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1 RESULTS: The involvement of CYP2B6 in artemisinin metabolism was demonstrated by metabolism of artemisinin by recombinant CYP2B6, inhibition of artemisinin disappearance in human liver microsomes by orphenadrine (76%) and primary inclusion of CYP2B6 in the tree-based regression model. Orphenadrine cytochrome P450 family 2 subfamily B member 6 Homo sapiens