Title : Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.

Pub. Date : 1999 Nov 23

PMID : 10569939






1 Functional Relationships(s)
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Protein Name
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1 Homocamptothecin (hCPT) contains a seven-membered beta-hydroxylactone in place of the conventional six-membered alpha-hydroxylactone ring found in camptothecin and its tumor active analogues, including topotecan and irinotecan. Topotecan choline phosphotransferase 1 Homo sapiens