Title : Production of superoxide and TNF-alpha from alveolar macrophages is blunted by glycine.

Pub. Date : 1999 Nov

PMID : 10564180






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Production of superoxide and TNF-alpha from alveolar macrophages is blunted by glycine. Glycine tumor necrosis factor Homo sapiens
2 Glycine blunts lipopolysaccharide (LPS)-induced increases in intracellular calcium concentration ([Ca(2+)](i)) and tumor necrosis factor-alpha (TNF-alpha) production by Kupffer cells through a glycine-gated chloride channel. Glycine tumor necrosis factor Homo sapiens
3 Glycine blunts lipopolysaccharide (LPS)-induced increases in intracellular calcium concentration ([Ca(2+)](i)) and tumor necrosis factor-alpha (TNF-alpha) production by Kupffer cells through a glycine-gated chloride channel. Glycine tumor necrosis factor Homo sapiens
4 The ability of glycine to prevent endotoxin [lipopolysaccharide (LPS)]-induced increases in [Ca(2+)](i) and subsequent production of superoxide and TNF-alpha in alveolar macrophages was examined. Glycine tumor necrosis factor Homo sapiens
5 Moreover, TNF-alpha production was also inhibited by glycine and also required nearly 10 microM glycine for half-inhibition. Glycine tumor necrosis factor Homo sapiens
6 Moreover, TNF-alpha production was also inhibited by glycine and also required nearly 10 microM glycine for half-inhibition. Glycine tumor necrosis factor Homo sapiens