Title : Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

Pub. Date : 1999 Oct 1

PMID : 10521394






2 Functional Relationships(s)
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1 We report that trichostatin A (TSA), an inhibitor of histone deacetylases (HDACs), abrogates the ability of p53 to repress the transcription of two genes that it negatively regulates, Map4 and stathmin. trichostatin A tumor protein p53 Homo sapiens
2 We report that trichostatin A (TSA), an inhibitor of histone deacetylases (HDACs), abrogates the ability of p53 to repress the transcription of two genes that it negatively regulates, Map4 and stathmin. trichostatin A tumor protein p53 Homo sapiens