Pub. Date : 1999 Oct 8
PMID : 10518015
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The guanine nucleotide exchange factor (GEF) Dbl targets Rho family proteins thereby stimulating their GDP/GTP exchange, and thus is believed to be involved in receptor-mediated regulation of the proteins. | Guanosine Diphosphate | MCF.2 cell line derived transforming sequence | Homo sapiens |
| 2 | However, GEF activity of Dbl toward Rho as measured by in vitro GDP binding assays remained unaffected following Gbetagamma binding, suggesting that additional signals may be required for the regulation of Dbl. | Guanosine Diphosphate | MCF.2 cell line derived transforming sequence | Homo sapiens |