Title : Resolution, absolute stereochemistry and molecular pharmacology of the enantiomers of ATPA.

Pub. Date : 1999 Sep 10

PMID : 10513575






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 has previously been shown to be a relatively weak AMPA receptor agonist and a very potent agonist at the GluR5 subtype of kainic acid-preferring (S)-glutamic acid ((S)-Glu) receptors. Kainic Acid glutamate ionotropic receptor kainate type subunit 1 Rattus norvegicus
2 Due to desensitization of GluR5 receptors, which could not be fully prevented by treatment with concanavalin A, (S)-ATPA-induced agonist effects were normalized to those of kainic acid. Kainic Acid glutamate ionotropic receptor kainate type subunit 1 Rattus norvegicus