Title : NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species.

Pub. Date : 1999 Oct 15

PMID : 10510285






1 Functional Relationships(s)
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1 Similarly, diphenyleneiodonium chloride, which inhibits NADPH-dependent electron transfer, prevented the degradation of CYP2E1, as did 4-methylpyrazole, a ligand which increases the level of CYP2E1. diphenyleneiodonium 2,4-dienoyl-CoA reductase 1 Homo sapiens