Title : Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: role of nicotinic receptors in the ventral tegmental area.

Pub. Date : 1999 Oct

PMID : 10481840






1 Functional Relationships(s)
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1 The nAChR antagonist mecamylamine administered systemically in chronically nicotine-treated rats elicits a behavioral withdrawal syndrome concomitant with a reduced DA output in the nucleus accumbens (NAC). Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus