Title : The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses.

Pub. Date : 1999 Sep 15

PMID : 10477278






1 Functional Relationships(s)
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1 Using labelled dihydrosphingosine and dihydrosphingosine-1-P (DHS-1-P), we found that overexpression of YSR2 significantly increased ceramide formation, whereas deletion of YSR2, YSR3, or both, accumulated DHS-1-P, and deletion of YSR2 decreased ceramide formation. safingol sphinganine kinase LCB3 Saccharomyces cerevisiae S288C