Title : Enzymatic rationale and preclinical support for a potent protein kinase C beta inhibitor in cancer therapy.

Pub. Date : 1999

PMID : 10470381






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 The macrocyclic bisindolylmaleimide, LY333531, selectively inhibits protein kinase C beta 1 and beta 2 isoforms with an approximate IC50 of 5 nanomolar. ruboxistaurin potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens