Title : Effect of all-trans retinoic acid on chemotherapy induced apoptosis and down-regulation of Bcl-2 in human myeloid leukaemia CD34 positive cells.

Pub. Date : 1999 Aug

PMID : 10456672






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both cytarabine and fludarabine induced a dose dependent increase in the number of apoptotic cells in both CD34 positive cell types. fludarabine CD34 molecule Homo sapiens
2 Using a quantitative ELISA assay, the Bcl-2 protein concentration was reduced by 86 or 100%, after 72 h of treatment with 10 microM cytarabine or fludarabine, respectively, in both CD34 positive leukaemia cell types. fludarabine CD34 molecule Homo sapiens