Pub. Date : 1999 Jul
PMID : 10455256
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Application to rats of a transdermal patch that releases doses of nitroglycerin comparable to those used in man (40, 80, 160 and 400 ng min(-1) rat(-1)) reduced gastric damage induced by indomethacin (25 mg kg(-1), p.o. | Nitroglycerin | CD59 molecule (CD59 blood group) | Homo sapiens |
| 2 | The nitroglycerin patch (160 ng min(-1) rat(-1)) also diminished damage by oral administration (1 ml) of acidified bile salts (100 mg kg(-1) taurocholic acid in 150 mM HCl) or 50% ethanol. | Nitroglycerin | CD59 molecule (CD59 blood group) | Homo sapiens |
| 3 | Transdermal nitroglycerin (160 ng min(-1) rat(-1)) did not influence basal gastric blood flow, as measured by lasser-doppler flowmetry, but prevented its reduction by indomethacin. | Nitroglycerin | CD59 molecule (CD59 blood group) | Homo sapiens |
| 4 | Transdermal nitroglycerin (160 ng min(-1) rat(-1)) prevented in vivo leukocyte rolling and adherence in the rat mesentery microvessels superfused with indomethacin, as evaluated by intravital microscopy. | Nitroglycerin | CD59 molecule (CD59 blood group) | Homo sapiens |