Title : Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function.

Pub. Date : 1999 Aug 27

PMID : 10452902






2 Functional Relationships(s)
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Protein Name
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1 Activation of these subunits occurs during late assembly stages through intramolecular precursor autolysis removing propeptides attached to Thr1, which then serves as N-terminal nucleophile in substrate hydrolysis. propeptides homoserine kinase Saccharomyces cerevisiae S288C
2 Thus, one role for the propeptides of active beta-type subunits might be to protect the mature subunits catalytic Thr1 alpha-amino group from acetylation. propeptides homoserine kinase Saccharomyces cerevisiae S288C