Title : Higher activity of 8-oxo-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) coincides with lower background levels of 8-oxo-2'-deoxyguanosine in DNA of fetal compared with maternal mouse organs.

Pub. Date : 1999 Jul

PMID : 10443924






2 Functional Relationships(s)
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1 Higher activity of 8-oxo-2"-deoxyguanosine 5"-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) coincides with lower background levels of 8-oxo-2"-deoxyguanosine in DNA of fetal compared with maternal mouse organs. 8-ohdg nudix (nucleoside diphosphate linked moiety X)-type motif 1 Mus musculus
2 Mammalian homologues of Escherichia coli MutT, a protein having 8-oxo-2"-deoxyguanosine 5"-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity, are thought to play the same role in preventing the incorporation of promutagenic 8-oxo-2"-deoxyguanosine (8-oxo-dG) into DNA. 8-ohdg nudix (nucleoside diphosphate linked moiety X)-type motif 1 Mus musculus