Pub. Date : 1999 Jul
PMID : 10428299
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NK-104, a potent 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, decreases apolipoprotein B-100 secretion from Hep G2 cells. | pitavastatin | apolipoprotein B | Homo sapiens |
| 2 | The effect of compound NK-104 was studied, a new competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG CoA-reductase), on apo B-100 synthesis and secretion from the human hepatoma cell line Hep G2. | pitavastatin | apolipoprotein B | Homo sapiens |
| 3 | It is speculated that the ability of compound NK-104 to decrease apo B-100 secretion from Hep G2 cells is due to a decreased intracellular cholesterol availability. | pitavastatin | apolipoprotein B | Homo sapiens |