Pub. Date : 1999 Jul
PMID : 10394958
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Up-regulation of ICH-1L protein by thromboxane A2 antagonists enhances cisplatin-induced apoptosis in non-small-cell lung-cancer cell lines. | Cisplatin | caspase 2 | Homo sapiens | ||
| 2 | Ice and Ced-3 homolog (ICH-1L) expression was significantly lower in PC-9/CDDP and was up-regulated by S-1452 or ONO-NT-126. | Cisplatin | caspase 2 | Homo sapiens | ||
| 3 | These data suggest that ICH-1L might play a critical role in cisplatin-induced apoptosis and that TXA2 blockade up-regulates ICH-1L protein expression. | Cisplatin | caspase 2 | Homo sapiens | ||